Medical Centric

Narcolepsy: Symptoms, Types, Causes, and Treatment

Narcolepsy

  • Narcolepsy is a nerve condition that can cause abnormal sleep, affecting your quality of life.
  • Although it is rare, narcolepsy is a chronic condition that is often misdiagnosed for something else and not given the right treatment.
  • It usually occurs in people between the ages of 10 and 25, with experts suggesting that 1 in 2000 people face narcolepsy.
  • The disease is defined by “sleep attacks” during the day and poor or patchy sleep at night.
  • In some cases, narcolepsy can even cause loss of muscle of control.
  • Although not fatal by itself, narcolepsy attacks can lead to accidents that can prove to be life-threatening.
  • Here’s everything you need to know about this nerve problem:

Symptoms

 

EDS
  • The most prominent symptom of narcolepsy is drowsiness during the day.
  • Known as excessive daytime sleepiness (EDS), narcolepsy brings with it an overwhelming need to sleep, in what is known as a “sleep attack”.
  • EDS makes it overwhelmingly difficult to function properly during the day.
Cataplexy
  • Late into its disease cycle, narcolepsy can cause loss of muscle tone or temporary loss of muscle function.
  • Known as cataplexy, the condition can cause problems ranging from droopy eyelids to total loss of body function.
  • Anti-depressant medication can suppress cataplexy.
Poor REM Sleep
  • Another symptom of narcolepsy is poorly regulated REM sleep, which can cause fragmented sleep.
  • Instead of occurring at night, REM sleep occurs at any time of day for people suffering from narcolepsy.
Sleep Paralysis
  • Narcolepsy can also cause regular bouts of sleep paralysis, mimicking the paralysis seen during REM sleep.
Hallucinations
  • Finally, you might have to face hallucinations during narcolepsy.
  • These hallucinations typically occur when falling asleep or waking up.

Types

  • There are two types of narcolepsy, with the distinction being the occurrence of cataplexy.
  • Type 1 narcolepsy is more common and leads to the development of cataplexy.
  • Cataplexy causes a loss in muscle tone and bouts of extreme sleepiness during the day.
  • Both symptoms occur due to a lack or low levels of a protein known as hypocretin (also known as oxerin).
  • Type 2 narcolepsy does not lead to the development of cataplexy due to the body having normal levels of hypocretin.

Causes

  • The primary driver behind type 1 narcolepsy is a low amount of hypocretin in the brain.
  • Hypocretin is believed to be responsible for regulating sleep cycles.
  • However, there is no known cause for this.
  • Experts believe gene mutations, autoimmune disorders, stress, infections, exposure to toxins to be primary causes for narcolepsy.
  • Furthermore, a family history of narcolepsy can increase your chances of getting the disease.

Diagnosis

  • Narcolepsy is characterized by disturbed sleep, and a medical professional can diagnose it with sleep evaluations such as a polysomnogram.
  • Blood and spinal fluid tests may also be conducted.
  • However, narcolepsy is often misdiagnosed due to its less definitive symptoms.

Treatment

  • Narcolepsy does not have a cure, with treatments making it easier for you to manage the disease.
  • Medication for narcolepsy includes stimulants, antidepressants, and anti-allergens.