NASOPHARYNGEAL CARCINOMA
- Nasopharyngeal carcinoma (also known as NPC) is a rare tumor of the head and neck which originates in the nasopharynx.
- The nasopharynx is located at the very back of the nose near the Eustachian tubes.
- Nasopharyngeal carcinoma is rare in the United States. It occurs much more frequently in other parts of the world — specifically Southeast Asia.
- Nasopharyngeal carcinoma is difficult to detect early.
- That’s probably because the nasopharynx isn’t easy to examine and symptoms of nasopharyngeal carcinoma mimic those of other, more-common conditions.
SYMPTOMS
Some symptoms of NPC are:
- Enlarged lymph node in the neck
- Bleeding from the nose or mouth
- Difficulty popping ears: This is due to close proximity of the tumor to the Eustachian tube, resulting in blockage and accumulation of fluid in the middle ear.
- Difficulty breathing through the nose
CAUSES
- Cancer begins when one or more genetic mutations cause normal cells to grow out of control, invade surrounding structures and eventually spread (metastasize) to other parts of the body.
- In nasopharyngeal carcinomas, this process begins in the squamous cells that line the surface of the nasopharynx.
- Exactly what causes the gene mutations that lead to nasopharyngeal carcinoma isn’t known.
DIAGNOSIS AND TREATMENT
Some diagnosis that a doctor may carry out are:
- Exam using a camera to see inside your nasopharynx.
- Physical exam.
- Test to remove a sample of suspicious cells.
Once the diagnosis is confirmed, your doctor orders other tests to determine the extent (stage) of the cancer, such as imaging tests.
Imaging tests may include:
- Computerized tomography (CT)
- Magnetic resonance imaging (MRI)
- Positron emission tomography (PET)
- X-ray
Treatments for NPC are:
- Chemotherapy
- Radiation
- Surgery
PREVENTION
- If you’re concerned about your risk of nasopharyngeal carcinoma, you may consider avoiding habits that have been associated with the disease.
- For instance, you may choose to cut back on the number of salt-cured foods you eat or avoid these foods altogether.