Medical Centric

NASOPHARYNGEAL CARCINOMA

NASOPHARYNGEAL CARCINOMA

  • Nasopharyngeal carcinoma (also known as NPC) is a rare tumor of the head and neck which originates in the nasopharynx.
  • The nasopharynx is located at the very back of the nose near the Eustachian tubes.
  • Nasopharyngeal carcinoma is rare in the United States. It occurs much more frequently in other parts of the world — specifically Southeast Asia.
  • Nasopharyngeal carcinoma is difficult to detect early.
  • That’s probably because the nasopharynx isn’t easy to examine and symptoms of nasopharyngeal carcinoma mimic those of other, more-common conditions.

SYMPTOMS

Some symptoms of NPC are:

  • Enlarged lymph node in the neck
  • Bleeding from the nose or mouth
  • Difficulty popping ears: This is due to close proximity of the tumor to the Eustachian tube, resulting in blockage and accumulation of fluid in the middle ear.
  • Difficulty breathing through the nose

CAUSES

  • Cancer begins when one or more genetic mutations cause normal cells to grow out of control, invade surrounding structures and eventually spread (metastasize) to other parts of the body.
  • In nasopharyngeal carcinomas, this process begins in the squamous cells that line the surface of the nasopharynx.
  • Exactly what causes the gene mutations that lead to nasopharyngeal carcinoma isn’t known.

DIAGNOSIS AND TREATMENT

Some diagnosis that a doctor may carry out are:

  • Exam using a camera to see inside your nasopharynx.
  • Physical exam.
  • Test to remove a sample of suspicious cells.

Once the diagnosis is confirmed, your doctor orders other tests to determine the extent (stage) of the cancer, such as imaging tests.

Imaging tests may include:

  • Computerized tomography (CT)
  • Magnetic resonance imaging (MRI)
  • Positron emission tomography (PET)
  • X-ray

Treatments for NPC are:

  • Chemotherapy
  • Radiation
  • Surgery

PREVENTION

  • If you’re concerned about your risk of nasopharyngeal carcinoma, you may consider avoiding habits that have been associated with the disease.
  • For instance, you may choose to cut back on the number of salt-cured foods you eat or avoid these foods altogether.